Sepsis

Sepsis

Organ dysfunction caused by dysregulated host response to suspected or proven infection as evidenced by:
  • Altered mental state
  • hypoxia
  • reduced urine output
  • tacharrythmia
  • peripherally shutdown
  • low BP
  • skin changes
  • coagulopathy
  • thrombocytopenia
  • acidosis
  • high lactate
  • hyperbilirubinaemia

Septic Shock

Persistent hypotension refractory to volume resuscitation, often with serum lactate >2mmol/Land requires vasopressors to maintain MAP >65mmHg.