Consideration should be given to rationalising antibiotic prescriptions in accordance with good antimicrobial stewardship.Data from the Chelsea and Westminster cohort and nationally/internationally suggest less than 10%, and probably more than 5% have bacterial/fungal pulmonary co-infection on presentation. Some patients can (rarely) present with COVID-19 plus another systemic infection/sepsis.Prescribe according to local current guidelines.Last updated: December 2020.